Prerequisites: one year of biology (C2005-C2006) and Contemporary Biology Laboratory (C2501). This lab will explore various molecular biology techniques frequently utilized in modern molecular biology laboratories. The lab will consist of three modules: 1) Molecular verification of genetically modified organisms (GMOs); 2) Site-directed mutagenesis; and 3) PCR isolation, cloning, and analysis of the GAPDH gene. SCE and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar.  http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf