Host: Ishmail Abdus-Saboor
Title: Mistakes Were Made: How To Fix Preclinical (Pain) Research
Abstract: Recent decades have seen an explosion in our understanding of the molecular and cellular underpinnings of pain, but this knowledge has not resulted in many new clinical therapies. I believe that one major reason for preclinical-to-clinical translational failure in the pain field, and more broadly, stems from poor subject and experimental design choices made by preclinical scientists in the name of research efficiency. This talk will detail how the choice of genetic background, sex, age/duration of injury, and laboratory environmental factors can profoundly alter the conclusions of preclinical experiments.
Hybrid seminar. Limited in-person attendance in room 601 Fairchild. Others are encouraged to join over Zoom. Please email [email protected] for a Zoom link for this seminar.