Senior Research Associate
Molecular Neurobiology Laboratory
Salk Institute of Biological Studies
Host: Darcy Kelley
Title: Towards an understanding of inhibitory neuron diversity in limb and thoracic spinal circuits
Abstract: Motor output varies along the rostro-caudal axis of the spinal cord. At limb levels, pairs of muscles flex and extend about each joint to coordinate running and grasping. In contrast, at thoracic levels, torso muscles supports posture, inspiration and expiration. In both the developing mouse and frog, we have examined how local inhibitory neurons vary at limb and thoracic levels during development. Our studies reveal molecular diversity of inhibitory neurons that is conserved between tetrapods and associated with differential motor output.