Hematopoietic stem cells in normal and malignant hematopoiesis
Faculty - PhD Program
Novel computational methods in human genetics
Structure & function of the p53 tumor suppressor protein.
Growth factor regulation of gene expression.
Population and human genetics
Yeast genetics; mechanisms of genetic recombination; control of genome stability; functional genomics.
Imaging and Modeling Biology at Physical Extremes.
JAK-STAT signaling and immune response
Evolutionary and population genetics of adaptation and disease
Molecular mechanisms of pattern formation and cellular differentiation during mouse embryogenesis; Organogenesis and regeneration of the prostate gland; Mouse models of prostate cancer.
Our laboratory aims to understand how specific circadian-regulated physiological functions (such as innate immunity, metabolism, and sleep) contribute to health and disease using Drosophila melanogaster.
Molecular studies of ion channel structure and function; synaptic transmission and plasticity in the mammalian brain
Diagramming disease networks with chemical and biological tools.
Developmental genetics in Drosophila
Yeast recombination studies in Saccharomyces cerevisiae
Statistics: stochastic computation, approximate Bayesian computation, data science, computational biology, statistical bioinformatics.
Principles of cellular adaptation
We develop and apply molecular, optical and data analytic methods for multi-scale understanding of complex biological systems.
Structural biology of proteins involved in RNA processing and quality control, and enzymes involved in human diseases (obesity, diabetes, cancer).
Evolution of cell types and circuits in the vertebrate brain.
Motor proteins in axonal transport, brain developmental disease, and synaptic function
The use of Stem Cells to Study the Development and Function of the Nervous System
Structure, function, regulation and cell biology of ion channels.
Development and function of the cortical microcircuitry.
500 Fairchild Center
Mail Code 2401
1212 Amsterdam Avenue
New York, NY 10027